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The Optilumereg; benign prostatic hyperplasia BPH drug-device system provides durable improvements in urinary flow and lower urinary tract symptoms LUTS for at least 3 years with low retreatment rates. Steven Kaplan, MD, of the Icahn School of Medicine at Mount Sinai, New York, New York, presented long-term follow-up data from 2 stanley shop Optilume studies at the American Urological Association AUA 2026 annual meeting in Washington, DC.To maintain patency, Optilume combines mechanical dilation of the prostatic urethra using a proprietary double-lobe balloon technology with local paclitaxel delivery. Long-term data from the pivotal PINNACLE sham-controlled trial and the EVEREST-I single-arm study support Optilumersquo durability as a minimally invasive therapy for at least 3 years with preserved urinary function and few additional interventions.The randomized, sham-controlled PINNACLE trial ClinicalTrials.gov identifier:NCT04131907 enrolled 148 participants across 18 centers in the US and Canada. Patients were randomized 2:1 to Optilume BPH n=100 or sham n=48 , with blinding maintained through 12 months. Long-term follow-up focused on the active-treatment cohort, with 69 patients completing 3-year assessment.In PINNACLE, urinary flow increase and symptom reduction were robust and sustained. The Qmax stanley becher rate nearly doubled, incre stanley italy asing from 8.9 mL/s to 17.1 mL/s. Paired analyses demonstrated minimal change between 12 months and 3 years, suggesting stabilization of therapeutic b Thvg Palestinians Killed in Protest Near Gaza-Israeli Border
The Randolph stanley quencher County Fair will open with a pair of pulling events Friday and Saturday night at the Moberly Motorsports Park. Fair Board President Jeff Alton says the new location stanley tumbler gives them flexibility for more variety 8230;.There was a demolition derby on the schedule this year, but it was canceled due to a scheduling conflict.In past years, 4-H exhibits were kept in The Lodge for viewing through the week. Alton says they won ;t be able to do the same this year 8230;..The Garden Tractor Pull will begin at 6:00 Friday. The Missouri Farmer Pullers will take to the track on Saturday night at 7:00. The Randolph County Fair will wrap up next Friday, July 21st, with the Auction Dinner and Livestock Auction.Related ContentDowning couple facing burglary and property damage charges in Schuyler County23 hours agoHannibal man charged with domestic assault23 hours agoIllinois man arrested in Boone County hatchet attack1 day a stanley polska goBoil advisory to be issued in Moberly1 day ago CareersAdvertise With UsContact UsPrivacy PolicyTerms Of UseAccessibility StatementContest RulesEEO ReportKTCM Public Inspection FileIf you have a disability preventing you from viewing this file, please contact [email 160;protected]KIRK Public Inspection FileIf you have a disability preventing you from viewing this file, please contact [email 160;protected]KRES Public Inspection FileIf you have a disability preventing you from viewing this file, please contact [email
The Optilumereg; benign prostatic hyperplasia BPH drug-device system provides durable improvements in urinary flow and lower urinary tract symptoms LUTS for at least 3 years with low retreatment rates. Steven Kaplan, MD, of the Icahn School of Medicine at Mount Sinai, New York, New York, presented long-term follow-up data from 2 stanley shop Optilume studies at the American Urological Association AUA 2026 annual meeting in Washington, DC.To maintain patency, Optilume combines mechanical dilation of the prostatic urethra using a proprietary double-lobe balloon technology with local paclitaxel delivery. Long-term data from the pivotal PINNACLE sham-controlled trial and the EVEREST-I single-arm study support Optilumersquo durability as a minimally invasive therapy for at least 3 years with preserved urinary function and few additional interventions.The randomized, sham-controlled PINNACLE trial ClinicalTrials.gov identifier:NCT04131907 enrolled 148 participants across 18 centers in the US and Canada. Patients were randomized 2:1 to Optilume BPH n=100 or sham n=48 , with blinding maintained through 12 months. Long-term follow-up focused on the active-treatment cohort, with 69 patients completing 3-year assessment.In PINNACLE, urinary flow increase and symptom reduction were robust and sustained. The Qmax stanley becher rate nearly doubled, incre stanley italy asing from 8.9 mL/s to 17.1 mL/s. Paired analyses demonstrated minimal change between 12 months and 3 years, suggesting stabilization of therapeutic b Thvg Palestinians Killed in Protest Near Gaza-Israeli Border
The Randolph stanley quencher County Fair will open with a pair of pulling events Friday and Saturday night at the Moberly Motorsports Park. Fair Board President Jeff Alton says the new location stanley tumbler gives them flexibility for more variety 8230;.There was a demolition derby on the schedule this year, but it was canceled due to a scheduling conflict.In past years, 4-H exhibits were kept in The Lodge for viewing through the week. Alton says they won ;t be able to do the same this year 8230;..The Garden Tractor Pull will begin at 6:00 Friday. The Missouri Farmer Pullers will take to the track on Saturday night at 7:00. The Randolph County Fair will wrap up next Friday, July 21st, with the Auction Dinner and Livestock Auction.Related ContentDowning couple facing burglary and property damage charges in Schuyler County23 hours agoHannibal man charged with domestic assault23 hours agoIllinois man arrested in Boone County hatchet attack1 day a stanley polska goBoil advisory to be issued in Moberly1 day ago CareersAdvertise With UsContact UsPrivacy PolicyTerms Of UseAccessibility StatementContest RulesEEO ReportKTCM Public Inspection FileIf you have a disability preventing you from viewing this file, please contact [email 160;protected]KIRK Public Inspection FileIf you have a disability preventing you from viewing this file, please contact [email 160;protected]KRES Public Inspection FileIf you have a disability preventing you from viewing this file, please contact [email
